How to use SeraSeal

Overview

SeraSeal® is applied topically to the bleeding site, and NEVER injected into the vascular system. After applying the hemostatic agent leave it undisturbed for 1 minute. Do not wipe. Work in another area during this 1 minute period while the fibrin strands cross-link to create a stronger tensile strength clot.  After a minute, irrigate or gently dab the fibrin clot to check for any hidden bleeding.  If there is a hidden bleed, repeat the above process.

SeraSeal® on Venous Bleeding

SeraSeal® is a new technical product for professional use. Physicians have been taught to deal with bleeding in traditional ways.  SeraSeal® is not traditional. It introduces new ways of controlling bleeding. Properly applied, SeraSeal® reliably arrests venous bleeds in seconds.

Before applying SeraSeal® to a bleeding wound, it is essential to locate the point origin of the bleed.  This may require the removal of any pooled blood in the wound through suction or absorption onto a surgical sponge.

Surface bleeds: Apply SeraSeal® drop wise to the surface of the bleeding site until bleeding stops.  Note:  A visual sign of hemostasis has occurred is when the blood becomes a brighter red.  Adding more SeraSeal® after hemostasis has occurred will wash the erythrocytes off the fibrin clot, giving the elusion of an active bleed.

Lacerations or incisions: First apply SeraSeal® to the base of the wound, continually applying the agent as you draw it up from the wound.  This assures the arrest of hemorrhage below the surface.  No local pressure is needed.  Do Not Wipe.  Wiping will remove the fibrin clot and reintroduce bleeding.  Instead, wait 60 seconds to allow the fibrin strands to cross-link.  This will give greater tensile strength to the fibrin clot.  After 1 minute, irrigate the wound to confirm no hidden bleeding.

SeraSeal ® on Arterial Bleeding

There are two different methods used to arrest the two types of an arterial hemorrhage.

Transected Artery: Apply SeraSeal® at a right angle and at a superior point to the proximal artery in quick drop succession.  Each drop will cascade around the peripheral opening of the artery, causing fibrin clot formation to begin at the outer edges.  With each drop the opening will get smaller and smaller until the fibrin clot seals off the wound.

Longitudinal Arterial Wound: Starting at the proximal end of the injured artery, apply SeraSeal® at a right angle in quick drop succession, moving distally as you apply the hemostatic agent.  This approach is like closing a zipper.  No local pressure is needed.  Do Not Wipe.  Wiping will remove the fibrin clot and reintroduce bleeding.  Instead, wait 60 seconds to allow the fibrin strands to cross-link.  This will give greater tensile strength to the fibrin clot.  After 1 minute, irrigate the wound to confirm no hidden bleeding.