SeraSeal Comparison

Overview

The effectiveness of SeraSeal® compared to fibrin glues and collagen/fibrin patches in 4 levels of hemorrhage intensity in normal and anticoagulant patients:

 

The effectiveness of SeraSeal® in 13 surgical categories:

Comparison table of hemostatic agents in use:

HEMOSTATIC AGENTS
Device
Class
Time to Hemostasis
Used Battlefield
Used Clinical
Direct
Pressure
Required
Inflammation
Ischemia
Adhesions
Tissue
Loss
Other
Cauterization Primary v: 1-2 sec No Yes No Yes Yes Yes Yes  
a: 1-2 sec
Suture/

Staple

Primary v: 1-5 sec No Yes No Yes No Yes No  
a: 1-5 sec
Direct

Pressure

Primary v: 1-3 min Yes Yes Yes No No No No  
a: 5-10 min
QuikClot

Zeolite

Adjunct v: 1-3 min Yes* No Yes Yes Yes Yes Yes  
a: 3-5 min
Trauma Dex

Polysaccharide

Adjunct v: 1-3 min Yes* No Yes No No No No  
ca: 5-10 min
HemCon

Chitosan

Adjunct v: 1-3 min Yes* No Yes Yes No Yes No Iodine
ca: 5-10 min
Celox

Chitosan

Adjunct v: 1-3 min Yes* No Yes Yes No Yes No Iodine
ca: 5-10 min
Evithrom

Fibrin Glue

Adjunct v: 1-3 min No Yes No Yes No Yes No  
sa: 5-10 min
Tisseel

Fibrin Glue

Adjunct v: 1-3 min No Yes No Yes No Yes No  
sa: 5-10 min
FloSeal

Fibrin Glue

Adjunct v: 1-3 min No Yes No Yes No Yes No  
sa: 5-10 min
CoSeal

Fibrin Glue

Adjunct v: 1-3 min No Yes No Yes No Yes No  
sa: 5-10 min
Surgicel

Collagen

Adjunct v: 1-5 min No Yes No Yes No Yes No  
ca: > 10 min
NovoSeven

Factor VIIa

Adjunct v: 1-3 min No Yes Yes No No Yes No DIC
a: 3-5 min
 

SeraSeal®

Primary v: 1-2 sec Yes Yes No No No No No  
a: < 10 sec
* = applied only to extremities        v = venous      a = arteries      ca = capillary arteries
sa = small artery