SeraSeal, In Comparison – Wortham Laboratories

Comparison table of hemostatic agents in use:

HEMOSTATIC AGENTS
Device	Class	Time to Hemostasis	Used Battlefield	Used Clinical	Direct Pressure Required	Inflammation	Ischemia	Adhesions	Tissue Loss	Other
Cauterization	Primary	v: 1-2 sec	No	Yes	No	Yes	Yes	Yes	Yes
		a: 1-2 sec
Suture/ Staple	Primary	v: 1-5 sec	No	Yes	No	Yes	No	Yes	No
		a: 1-5 sec
Direct Pressure	Primary	v: 1-3 min	Yes	Yes	Yes	No	No	No	No
		a: 5-10 min
QuikClot Zeolite	Adjunct	v: 1-3 min	Yes*	No	Yes	Yes	Yes	Yes	Yes
		a: 3-5 min
Trauma Dex Polysaccharide	Adjunct	v: 1-3 min	Yes*	No	Yes	No	No	No	No
		ca: 5-10 min
HemCon Chitosan	Adjunct	v: 1-3 min	Yes*	No	Yes	Yes	No	Yes	No	Iodine
		ca: 5-10 min
Celox Chitosan	Adjunct	v: 1-3 min	Yes*	No	Yes	Yes	No	Yes	No	Iodine
		ca: 5-10 min
Evithrom Fibrin Glue	Adjunct	v: 1-3 min	No	Yes	No	Yes	No	Yes	No
		sa: 5-10 min
Tisseel Fibrin Glue	Adjunct	v: 1-3 min	No	Yes	No	Yes	No	Yes	No
		sa: 5-10 min
FloSeal Fibrin Glue	Adjunct	v: 1-3 min	No	Yes	No	Yes	No	Yes	No
		sa: 5-10 min
CoSeal Fibrin Glue	Adjunct	v: 1-3 min	No	Yes	No	Yes	No	Yes	No
		sa: 5-10 min
Surgicel Collagen	Adjunct	v: 1-5 min	No	Yes	No	Yes	No	Yes	No
		ca: > 10 min
NovoSeven Factor VIIa	Adjunct	v: 1-3 min	No	Yes	Yes	No	No	Yes	No	DIC
		a: 3-5 min
SeraSeal®	Primary	v: 1-2 sec	Yes	Yes	No	No	No	No	No
		a: < 10 sec
* = applied only to extremities v = venous a = arteries ca = capillary arteries sa = small artery